Type to search

Are you looking for the best glutathione supplement? When creating OGF: Original Glutathione Formula, Dr. Keller found the best results when adding in compounds that further promote glutathione production and offer more health benefits to you.

One of the components of OGF is NAC, short for N-Acetyl-Cysteine. NAC has become one of the most beneficial and popular immune support supplements, and part of this is because of its role in the production of glutathione, the body’s most important antioxidant.

Let’s discuss the connection between NAC and glutathione, and the benefits NAC offers you.

What is NAC?

NAC is an antioxidant that plays a significant role in supporting immune health. It accomplishes this by inhibiting oxidative stress, a detriment to the immune system and a substantial component of aging. By inhibiting oxidative stress, NAC helps the immune system function optimally.

However, one of the most important roles of NAC lies in its ability to produce other antioxidants, namely, glutathione.

NAC and Glutathione

NAC is vital for glutathione production because it is a precursor for it. This relationship starts with the consumption of NAC, which is then  absorbed by the gastrointestinal tract and sent to the liver. The liver then converts NAC into the amino acid cysteine, which it uses to produce glutathione.

So, when cysteine is low, the body does not have the initial compounds that eventually become glutathione.

The Benefits of NAC

NAC offers many benefits to the body, such as:


NAC is essential in the body’s detoxification process, which can improve liver or kidney function.  Its role in the detoxification process helps to protect against environmental toxins.

Mental Health

NAC plays a role in the regulation of glutamate, which is the most important neurotransmitter in the brain.

Improve Respiratory Function

NAC aids in the improvement of overall lung function. NAC is a powerful antioxidant that assists your lungs in eliminating toxins, pollutants and allergens that may cause health challenges.

Boost Brain Health

The ability of NAC to replenish glutathione in the body continues to show significant benefits, including in the brain. Specifically, glutathione helps reduce oxidative damage in brain cells, which is often associated with aging. Glutamate is another vital component in brain health, and it is involved in memory functions, learning, and behaviors.

Thus, NAC may help those with health challenges that affect the brain and memory because of its ability to replenish glutathione and regulate glutamate.

Improvement of heart function

Heart conditions are the leading cause of death worldwide, making its prevention a critical component of a healthy life. When heart tissue becomes challenged by oxidative stress, over time, damage to the heart can occur. However, NAC may help to reduce oxidative damage to the heart tissue, potentially lowering this risk.

NAC may also improve cardiovascular health because of its ability to increase nitric oxide production, which is a compound that dilates the veins and improves blood flow.

Improve Fertility

Infertility can be a difficult challenge for a couple who wishes for a child. However, NAC may be able to help with male infertility.

Research has found that male infertility often increases due to insufficient antioxidant levels. This is because free radical formation in the reproductive system can go unchecked, leading to oxidative stress that can cause cell death and reduced fertility.

See the NAC Advantage

NAC is a potent antioxidant that offers many benefits to the body, such as improving mental health, promoting respiratory function, reducing cardiovascular risk, improving infertility, and boosting brain health.

Additionally, NAC helps to produce glutathione, the most important antioxidant in the body that naturally declines as we age.

By using NAC in OGF: Original Glutathione Formula, you can increase your glutathione levels and experience the benefits of NAC in all aspects of your health. Give it a try today and see the NAC advantage.



Aremu, D., Madejczyk, M., & Ballatori, N. (2008). N -Acetylcysteine as a Potential Antidote and Biomonitoring Agent of Methylmercury Exposure. Environmental Health Perspectives, 116(1), 26-31. doi: 10.1289/ehp.10383
Mokhtari, V., Afsharian, P., Shahhoseini, M., Kalantar, S., & Moini, A. (2017). A Review on Various Uses of N-Acetyl Cysteine . Cell Journal (Yakhteh), 19(1), 11. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241507/
de Andrade, K., Moura, F., dos Santos, J., de Araújo, O., de Farias Santos, J., & Goulart, M. (2015). Oxidative Stress and Inflammation in Hepatic Diseases: Therapeutic Possibilities of N-Acetylcysteine. International Journal Of Molecular Sciences, 16(12), 30269-30308. doi: 10.3390/ijms161226225
Purves D, Augustine GJ, Fitzpatrick D, et al., editors. Neuroscience. 2nd edition. Sunderland (MA): Sinauer Associates; 2001. Glutamate. Available from: https://www.ncbi.nlm.nih.gov/books/NBK10807/
Sanguinetti, C. (2015). N-acetylcysteine in COPD: why, how, and when?. Multidisciplinary Respiratory Medicine, 11(1). doi: 10.1186/s40248-016-0039-2
Calverley, P., Rogliani, P., & Papi, A. (2020). Safety of N-Acetylcysteine at High Doses in Chronic Respiratory Diseases: A Review. Drug Safety, 44(3), 273-290. doi: 10.1007/s40264-020-01026-y
Stey, C., Steurer, J., Bachmann, S., Medici, T., & Tramer, M. (2000). The effect of oral N-acetylcysteine in chronic bronchitis: a quantitative systematic review. European Respiratory Journal, 16(2), 253-262. Retrieved from https://erj.ersjournals.com/content/16/2/253.short
Mokhtari, V., Afsharian, P., Shahhoseini, M., Kalantar, S. M., & Moini, A. (2017). A Review on Various Uses of N-Acetyl Cysteine. Cell journal, 19(1), 11–17. https://doi.org/10.22074/cellj.2016.4872
Costa, M., Bernardi, J., Fiuza, T., Costa, L., Brandão, R., & Pereira, M. (2016). N-acetylcysteine protects memory decline induced by streptozotocin in mice. Chemico-Biological Interactions, 253, 10-17. doi: 10.1016/j.cbi.2016.04.026
 Liu, C., Lu, X., Shen, M., Xing, C., Ma, J., Duan, Y., & Yuan, L. (2015). N-Acetyl Cysteine improves the diabetic cardiac function: possible role of fibrosis inhibition. BMC Cardiovascular Disorders, 15(1). doi: 10.1186/s12872-015-0076-3
 Anfossi, G., Russo, I., Massucco, P., Mattiello, L., Cavalot, F., & Trovati, M. (2001). N-acetyl-L-cysteine exerts direct anti-aggregating effect on human platelets. European Journal Of Clinical Investigation, 31(5), 452-461. doi: 10.1046/j.1365-2362.2001.00815.x
Lombardo, F., Sansone, A., Romanelli, F., Paoli, D., Gandini, L., & Lenzi, A. (2011). The role of antioxidant therapy in the treatment of male infertility: an overview. Asian Journal Of Andrology, 13(5), 690-697. doi: 10.1038/aja.2010.183






You Might also Like

Leave a Comment

Your email address will not be published. Required fields are marked *